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Risk Assessment Plots

18 Jul 2012 (Updated 16 Aug 2012)

Functions to calculate the NRI & IDI, difference in AUC & visualize the results

File Information
Description	Crucial to evaluating the value of a new biomarker (variable) to a pre-existing risk model is whether it increases the calculated risk of those with the disease (event/outcome) and decreases the calculated risk of those without. In the past 4 years two new statistics - the IDI and NRI have been proposed. Risk_Assessment_Plot calculates those stats along with several others and produces a plot to visualize them. I published an explanation of this plot and the associated metrics recently - it is available Open Access: http://cjasn.asnjournals.org/content/early/2012/05/24/CJN.09590911.full My first submission - perhaps not pretty, but useful I hope.
Required Products	Statistics Toolbox
MATLAB release	MATLAB 7.14 (R2012a)

Tags for This File
Everyone's Tags	area under the curve, auc, biomarkers, idi, integrated discrimination improvement, net reclassification improvement, nri, relative idi, sensitivity, specificity, statistics
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Updates
16 Aug 2012	It has been pointed out to me that the Risk Assessment Plots look like a combination of two "classification plots" previously described by Pepe et al. I have added an appropriate reference to the description of the plot.