How to make a GUI work with bluetooth simultaneously?to plot continuously the information received from bluetooth via communication with a microcontroller

I have created codes for both GUI and bluetooth. The codes run well independently. I am able to run the PAINT GUI i have created as well as connect and transmit values from micrcontroller to PC using the bluetooth module. The problem arises when I combine the 2 codes...If I put the bluetooth code anywhere in the GUI code..then the bluetooth module works....communication takes place but matlab does not generate the GUI window until and unless I close the bluetooth connection using fclose().

Please help because I want to receive coordinates from the microcontroller and plot them simultaneously on my GUI while using ceratin paint features like selecting a colour or brush or pencil. The major problem is the GUI is not getting created unless the connection is closed